Table 3 Hazard ratios for all-cause and cause-specific mortality, according to quintiles of fruits intake in a large prospective cohort study with 14 years of follow-up

Median intake

41.26

81.74

120.86

175.81

300.05

Person-years of follow-up

129310.88

131690.17

134424.09

135841.02

140298.02

All-cause mortality

 Mortality rate (per 1000 person-years)

19.6

17

14.4

14.9

14.6

 Model 1, HR (95% CI)

1

0.96(0.91, 1.01)

0.82(0.77, 0.87)

0.83(0.79, 0.88)

0.77(0.72, 0.81)

< 0.001

 Model 2, HR (95% CI)

1

0.99 (0.94, 1.06)

0.88(0.82, 0.93)

0.90(0.84, 0.96)

0.87(0.81, 0.93)

< 0.001

 Model 3, HR (95% CI)

1

1.0(0.95, 1.06)

0.89(0.83, 0.94)

0.91(0.86, 0.97)

0.89(0.83, 0.96)

< 0.001

All cancer cause

 Mortality rate (per 1000 person-years)

3.2

3.1

2.5

2.4

2.4

 Model 1, HR (95% CI)

1

1.06(0.93, 1.22)

0.83(0.72, 0.96)

0.81(0.70, 0.94)

0.76(0.70, 0.94)

< 0.001

 Model 2, HR (95% CI)

1

1.09(0.95, 1.25)

0.87(0.75, 1.01)

0.87(0.75, 1.01)

0.85(0.73, 0.99)

0.002

 Model 3, HR (95% CI)

1

1.07(0.93, 1.23)

0.85(0.73, 0.99)

0.83(0.71, 0.98)

0.80(0.67, 0.95)

< 0.001

GI cancer cause

 Mortality rate (per 1000 person-years)

1.8

1.9

1.1

1.3

1.3

 Model 1, HR (95% CI)

1

1.17(0.97, 1.40)

0.71(0.58, 0.87)

0.81(0.67, 0.99)

0.75(0.61, 0.91)

< 0.001

 Model 2, HR (95% CI)

1

1.19(0.99, 1.43)

0.75(0.60, 0.92)

0.87(0.71, 1.07)

0.86(0.70, 1.07)

0.01

 Model 3, HR (95% CI)

1

1.17(0.97, 1.41)

0.73(0.59, 0.90)

0.84(0.67, 1.03)

0.82(0.65, 1.03)

0.007

CVD cause

 Mortality rate (per 1000 person-years)

7

6.2

5

5.2

5.4

 Model 1, HR (95% CI)

1

0.98(0.90, 1.08)

0.82(0.74, 0.90)

0.86(0.78, 0.95)

0.87(0.79, 0.96)

< 0.001

 Model 2, HR (95% CI)

1

1.03(0.93, 1.13)

0.87(0.79, 0.97)

0.91(0.82, 1.01)

0.94(0.85, 1.04)

0.04

 Model 3, HR (95% CI)

1

1.03(0.94, 1.14)

0.88(0.79, 0.98)

0.91(0.82, 1.02)

0.94(0.83, 1.06)

0.07

Other cause

 Mortality rate (per 1000 person-years)

5.9

4.5

4.2

4.6

4.3

 Model 1, HR (95% CI)

1

0.86(0.77, 0.95)

0.81(0.73, 0.90)

0.88(0.80, 0.98)

0.77(0.69, 0.86)

< 0.001

 Model 2, HR (95% CI)

1

0.91(0.82, 1.02)

0.88(0.79, 0.99)

0.98(0.87, 1.09)

0.89(0.79, 1.00)

0.23

 Model 3, HR (95% CI)

1

0.92(0.82, 1.02)

0.89(0.80, 1.00)

0.99(0.88, 1.11)

0.91(0.80, 1.04)

0.49