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Table 1 Characteristics of study subjects

From: Hip circumference has independent association with the risk of hyperuricemia in middle-aged but not in older male patients with type 2 diabetes mellitus

Variable

Total (n = 1447)

Middle-Aged Group (n = 791)

Older Group (n = 656)

HUA (n = 279)

Non-HUA (n = 1168)

HUA (n = 146)

Non-HUA (n = 645)

HUA (n = 133)

Non-HUA (n = 523)

Age, y

64.0 (59.0–69.0)

63.0 (58.0–69.0)

59.5 (55.0–62.0)

59.0 (55.0–62.0)

69.0 (67.0–73.5)

70.0 (67.0–75.0)

Duration of T2DM, y

11.0 (6.0–19.0)

10.0 (4.0–16.0)**

10.0 (5.0–15.3)

9.0 (4.0–13.0)*

14.0 (8.0–20.0)

12.0 (5.0–20.0)

BMI, kg/m2

25.7 (24.0–27.5)

24.5 (22.5–26.4)**

25.8 (24.2–27.8)

24.6 (22.6–26.8)**

25.6 (23.6–27.4)

24.4 (22.3–26.1)**

WC, cm

96.0 (90.0–100.2)

92.0 (87.0–98.0)**

96.0 (89.8–102.0)

92.0 (87.0–98.0)**

96.0 (90.0–100.0)

92.0 (87.0–98.0)*

HC, cm

100.0 (94.0–104.0)

97.0 (92.0–101.8)**

100.0 (94.0–104.3)

97.0 (92.0–101.5)**

100.0 (95.0–103.5)

97.0 (92.0–102.0)*

WHR

0.96 (0.93–1.00)

0.96 (0.92–0.99)

0.96 (0.93–1.00)

0.96 (0.93–0.99)

0.96 (0.93–0.99)

0.96 (0.91–0.99)*

WHtR

0.56 (0.53–0.59)

0.54 (0.51–0.58)**

0.55 (0.52–0.59)

0.54 (0.51–0.57)**

0.57 (0.53–0.60)

0.54 (0.51–0.58)*

UA, mg/dl

7.7 (7.3–8.4)

5.3 (4.5–6.0)**

7.8 (7.4–8.5)

5.3 (4.5–6.1)**

7.6 (7.2–8.4)

5.3 (4.6–6.0)**

FPG, mg/dl

125.8 (106.7–155.1)

136.6 (110.1–172.5)**

125.9 (107.1–157.9)

142.0 (113.5–178.6)**

123.1 (104.3–152.8)

132.3 (106.8–167.4)

FINS, μIU/mL

9.7 (6.2–15.1)

8.4 (5.3–12.6)*

9.3 (5.8–13.9)

8.0 (5.0–12.0)*

10.7 (6.4–17.7)

9.1 (5.6- 13.3)*

HOMA-IR

3.0 (1.8–5.4)

2.9 (1.7–4.8)

2.9 (1.8–4.5)

2.9 (1.7–4.6)

3.2 (1.9–6.1)

3.0 (1.7–4.9)

HOMA-β

55.0 (34.4–101.0)

41.1 (23.1–75.6)**

50.2 (34.0–86.7)

36.7 (22.2–65.3)**

59.9 (34.9–130.8)

48.1 (25.0–93.9)*

ALT, U/L

19.0 (14.0–29.0)

18.0 (13.0–26.0)

21.0 (15.0–32.0)

19.0 (14.0–28.0)

18.0 (12.0–26.0)

17.0 (13.0–25.0)

AST, U/L

19.0 (16.0–24.0)

18.0 (15.0–23.0)*

19.0 (16.0–25.0)

18.0 (15.0–24.0)

20.0 (16.0–24.0)

18.0 (15.0–23.0)

TG, mg/dl

174.3 (123.0–268.1)

123.0 (87.6–183.2)**

187.6 (132.5–281.9)

132.7 (94.7–194.7)**

155.8 (113.7–238.9)

113.3 (81.4–162.0)**

TC, mg/dl

164.9 (135.1–190.3)

160.6 (136.7–188.8)

162.0 (136.7–191.1)

166.8 (141.9–195.4)

169.1 (134.2–188.2)

154.4 (129.3–180.0)

HDL-C, mg/dl

40.2 (35.1–46.3)

43.6 (37.5–51.1)**

40.0 (34.4–45.2)

43.6 (37.5–51.0)**

40.2 (35.7–47.1)

43.2 (37.5–51.4)*

LDL-C, mg/dl

96.5 (75.3–117.4)

92.3 (72.6–115.1)

97.1 (76.1–118.1)

96.9 (76.4–118.0)

96.5 (68.1–116.6)

88.4 (67.2–110.8)

eGFR, mL/min/1.37m2

93.5 (72.9–118.2)

119.7 (98.9–142.7)**

103.6 (76.7–122.4)

125.6 (106.6–149.7)**

87.0 (67.4–107.5)

112.2 (90.6–131.6)**

SBP, mm Hg

134.0 (126.0–149.0)

131.0 (125.0–146.0)

133.0 (125.0- 149)

130.0 (123.0–143.0)

135.0 (127.0–150.0)

134.0 (126.0–149.0)

DBP, mm Hg

75.0 (70.0–85.0)

75.0 (70.0–85.0)

77.0 (70.0–87.0)

78.0 (70.0–86.0

72.0 (70.0–83.0)

73.0 (69.0–81.0)

  1. Abbreviations: HUA Hyperuricemia, T2DM Type 2 diabetes mellitus, BMI Body mass index, WC Waist circumference, HC Hip circumference, WHR Waist-to-hip ratio, WHtR Waist-to-height ratio, UA Uric acid, FPG Fasting plasma glucose, FINS Fasting insulin, ALT Alanine aminotransferase, AST Aspartate aminotransferase, TG Triglycerides, TC Total cholesterol, HDL-C High-density lipoprotein cholesterol, LDL-C Low-density lipoprotein cholesterol, eGFR Estimated glomerular filtration rate, SBP Systolic blood pressure, DBP Diastolic blood pressure
  2. *Significance between HUA and non-HUA groups with T2DM (P < 0.05)
  3. **Significance between HUA and non-HUA groups with T2DM (P < 0.001)