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Table 5 Associations of marine PUFAs intake with all-cause mortality and CVD mortality

From: Association of marine PUFAs intakes with cardiovascular disease, all-cause mortality, and cardiovascular mortality in American adult male patients with dyslipidemia: the U.S. National Health and Nutrition Examination Survey, 2001 to 2016

 

Model 1

Model 2

Model 3

HRa

95% CIa

p-value

HRa

95% CIa

p-value

HRa

95% CIa

p-value

 

DPA

        

ALL-cause

 Q1

Ref

Ref

 

Ref

Ref

 

Ref

Ref

 

 Q2

0.84

0.71, 0.99

0.040*

0.88

0.75, 1.03

0.117

0.87

0.74, 1.02

0.088

 Q3

0.73

0.62, 0.86

 < 0.001**

0.76

0.64, 0.91

0.002**

0.77

0.64, 0.91

0.003**

CVD

 Q1

Ref

Ref

 

Ref

Ref

 

Ref

Ref

 

 Q2

0.80

0.62, 1.04

0.091

0.84

0.65, 1.08

0.167

0.84

0.65, 1.09

0.187

 Q3

0.64

0.49, 0.84

0.001**

0.67

0.51, 0.88

0.004**

0.68

0.52, 0.90

0.006**

 

DHA

        

ALL-cause

 Q1

Ref

Ref

 

Ref

Ref

 

Ref

Ref

 

 Q2

1.09

0.95, 1.26

0.221

1.11

0.96, 1.29

0.148

1.13

0.96, 1.32

0.142

 Q3

0.95

0.80, 1.12

0.509

0.96

0.80, 1.15

0.669

0.98

0.79, 1.20

0.832

CVD

 Q1

Ref

Ref

 

Ref

Ref

 

Ref

Ref

 

 Q2

1.08

0.86, 1.35

0.525

1.09

0.86, 1.38

0.463

1.09

0.85, 1.40

0.489

 Q3

0.88

0.70, 1.11

0.268

0.88

0.69, 1.13

0.325

0.89

0.67, 1.19

0.437

 

EPA

        

ALL-cause

 Q1

Ref

Ref

 

Ref

Ref

 

Ref

Ref

 

 Q2

0.92

0.79, 1.06

0.242

0.94

0.82, 1.08

0.389

0.92

0.80, 1.06

0.262

 Q3

0.84

0.71, 0.99

0.039*

0.89

0.74, 1.06

0.188

0.90

0.75, 1.08

0.252

CVD

 Q1

Ref

Ref

 

Ref

Ref

 

Ref

Ref

 

 Q2

0.85

0.66, 1.09

0.205

0.86

0.67, 1.12

0.263

0.87

0.66, 1.14

0.312

 Q3

0.78

0.61, 1.00

0.051

0.82

0.64, 1.05

0.120

0.84

0.65, 1.10

0.202

  1. * p < 0.05; **p < 0.01
  2. aHR hazard ratio, CI confidence interval, CVD CVD mortality, ALL-cause All-cause mortality; multivariate adjusted Cox proportional regression models of marine PUFAs intake with cardiovascular disease: Model 1: Age and race; Model 2: Model 1 + education, marital status, ratio of family income to poverty, BMI, physical activity, smoking status and alcohol consumption; Model 3: Model 2 + hypertension, diabetes, cancer, osteoarthritis, total energy intake, total fat intake, and total cholesterol intake