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Table 1 Characteristics of the UK Biobank cohort*

From: Association of sugar intake from different sources with incident dementia in the prospective cohort of UK Biobank participants

Parameters

Total cohort

(n = 186,622)

FS intake (%E) split by quintiles

0.0 to 6.8

(n = 37,325)

6.8 to 9.5

(n = 37,324)

9.5 to 12.1

(n = 37,324)

12.1 to 15.5

(n = 37,324)

15.5 to 77.5

(n = 37,325)

Characteristics

 Age at completion of first Oxford WebQ (years)

58 (8)

58 (8)

58 (8)

58 (8)

58 (8)

57 (8)

 BMI (kg/m2)

26.6 (4.3)

26.8 (4.4)

26.6 (4.3)

26.4 (4.2)

26.4 (4.3)

26.6 (4.4)

 Ethnic background

  - White

179,879 (96.4)

36,088 (96.7)

36,251 (97.1)

36,162 (96.9)

36,101 (96.7)

35,277 (94.5)

  - Mixed, Asian, Black, Chinese, and other

6,743 (3.6)

1,237 (3.3)

1,073 (2.9)

1,162 (3.1)

1,223 (3.3)

2,048 (5.5)

 General health status

  - Poor

4,515 (2.4)

814 (2.2)

697 (1.9)

725 (1.9)

873 (2.3)

1,406 (3.8)

  - Fair

29,894 (16.0)

5,985 (16.0)

5,544 (14.9)

5,499 (14.7)

5,877 (15.7)

6,989 (18.7)

  - Good

113,190 (60.7)

22,613 (60.6)

22,707 (60.9)

23,043 (61.7)

22,838 (61.2)

21,989 (58.9)

  - Excellent

39,023 (20.9)

7,913 (21.2)

8,376 (22.4)

8,057 (21.6)

7,736 (20.7)

6,941 (18.6)

 Highest qualification

  - None of the below

14,984 (8.0)

3,307 (8.9)

2,788 (7.5)

2,800 (7.5)

2,818 (7.6)

3,271 (8.8)

  - National exams at age 16 years

28,062 (15.0)

5,699 (15.3)

5,352 (14.3)

5,450 (14.6)

5,509 (14.8)

6,052 (16.2)

  - Vocational qualifications or optional national exams at ages 17–18 years

33,058 (17.7)

6,771 (18.1)

6,440 (17.3)

6,377 (17.1)

6,381 (17.1)

7,089 (19.0)

  - Professional

28,977 (15.5)

5,543 (14.9)

5,625 (15.1)

5,930 (15.9)

5,934 (15.9)

5,945 (15.9)

  - College or University

81,541 (43.7)

16,005 (42.9)

17,119 (45.9)

16,767 (44.9)

16,682 (44.7)

14,968 (40.1)

History of mental illnesses

12,278 (6.6)

2,413 (6.5)

2,288 (6.1)

2,222 (6.0)

2,409 (6.5)

2,946 (7.9)

Physical activity (MET-min/week)

4,130 (2,651)

4,069 (2,663)

4,112 (2,572)

4,133 (2,559)

4,142 (2,598)

4,194 (2,852)

SBP (mmHg)

139 (19)

139 (20)

139 (19)

139 (19)

138 (19)

138 (19)

Sex – female

106,834 (57.3)

21,447 (57.5)

21,731 (58.2)

21,512 (57.6)

21,380 (57.3)

20,764 (55.6)

 Smoking status

  - Never

107,357 (57.5)

19,187 (51.4)

20,906 (56.0)

21,870 (58.6)

22,713 (60.9)

22,681 (60.8)

  - Previous

65,874 (35.3)

15,128 (40.5)

13,972 (37.4)

13,146 (35.2)

12,165 (32.6)

11,463 (30.7)

  - Occasional

4,461 (2.4)

1,065 (2.9)

912 (2.4)

849 (2.3)

810 (2.2)

825 (2.2)

  - Current < 10 cigarettes per day

2,313 (1.2)

491 (1.3)

415 (1.1)

385 (1.0)

476 (1.3)

546 (1.5)

  - Current 10 to 14 cigarettes per day

2,011 (1.1)

410 (1.1)

349 (0.9)

332 (0.9)

361 (1.0)

559 (1.5)

  - Current 15 to 19 cigarettes per day

1,787 (1.0)

376 (1.0)

302 (0.8)

294 (0.8)

323 (0.9)

492 (1.3)

  - Current ≥ 20 cigarettes per day

2,819 (1.5)

668 (1.8)

468 (1.3)

448 (1.2)

476 (1.3)

759 (2.0)

 Total household income per year (k£)

  - < 18

24,987 (13.4)

4,730 (12.7)

4,582 (12.3)

4,692 (12.6)

5,101 (13.7)

5,882 (15.8)

  - 18 to < 31

40,795 (21.9)

7,767 (20.8)

7,956 (21.3)

8,176 (21.9)

8,333 (22.3)

8,563 (22.9)

  - 31 to < 52

48,423 (26.0)

9,591 (25.7)

9,806 (26.3)

9,779 (26.2)

9,669 (25.9)

9,578 (25.7)

  - 52 to < 100

41,708 (22.4)

9,877 (23.8)

8,751 (23.4)

8,469 (22.7)

8,179 (21.9)

7,432 (19.9)

  - ≥ 100

12,437 (6.7)

2,857 (7.7)

2,735 (7.3)

2,537 (6.8)

2,345 (6.3)

1,963 (5.3)

  - Unknown

18,272 (9.8)

3,503 (9.4)

3,494 (9.4)

3,671 (9.8)

3,697 (9.9)

3,907 (10.5)

  Townsend deprivation index

-1.6 (2.8)

-1.5 (2.9)

-1.7 (2.8)

-1.7 (2.8)

-1.8 (2.8)

-1.5 (2.9)

Dietary sugar subtype intake in %E

 Carbohydrates

48.6 (7.8)

44.4 (8.9)

46.8 (7.3)

48.4 (6.7)

50.1 (6.3)

53.5 (6.6)

 Total sugars

24.4 (7.2)

18.8 (6.6)

21.8 (5.6)

23.9 (5.3)

26.2 (5.2)

31.1 (6.3)

 Intrinsic sugars

13.0 (5.7)

14.4 (6.4)

13.6 (5.6)

13.1 (5.3)

12.5 (5.1)

11.4 (5.3)

 FS

11.4 (5.6)

4.5 (1.7)

8.2 (0.8)

10.8 (0.7)

13.7 (1.0)

19.7 (4.3)

 FS beverages

4.7 (4.7)

1.1 (1.4)

2.6 (2.1)

3.9 (2.5)

5.6 (3.1)

10.5 (5.9)

  - Soda/fruit drinks

1.6 (3.3)

0.2 (0.6)

0.5 (1.2)

0.9 (1.7)

1.6 (2.4)

4.6 (5.4)

  - Juice

2.1 (2.8)

0.6 (1.2)

1.4 (1.8)

2.1 (2.2)

2.7 (2.6)

3.8 (4.0)

  - Milk-based drinks

0.3 (0.9)

0.1 (0.5)

0.2 (0.7)

0.3 (0.9)

0.4 (1.0)

0.6 (1.3)

  - Tea/coffee

0.6 (1.6)

0.2 (0.6)

0.3 (1.0)

0.5 (1.2)

0.7 (1.6)

1.4 (2.6)

 FS solids

6.6 (3.5)

3.4 (1.8)

5.6 (2.1)

6.9 (2.5)

8.1 (3.0)

9.2 (4.1)

  - Treats

4.4 (3.0)

2.1 (1.6)

3.6 (2.0)

4.5 (2.4)

5.3 (2.8)

6.3 (3.8)

  - Cereals

0.5 (0.8)

0.3 (0.6)

0.5 (0.7)

0.5 (0.8)

0.6 (0.8)

0.6 (0.9)

  - Toppings

1.2 (1.6)

0.4 (0.9)

0.9 (1.4)

1.3 (1.6)

1.6 (1.8)

1.7 (2.0)

  - Sauces

0.3 (0.4)

0.2 (0.4)

0.3 (0.4)

0.3 (0.4)

0.3 (0.4)

0.3 (0.4)

Other nutrients of interest

 Alcohol (g/d)

17.3 (22.1)

26.1 (28.5)

20.2 (22.9)

16.7 (19.7)

13.7 (17.7)

9.7 (15.5)

 Fat (g/d)

79.3 (28.0)

73.9 (27.4)

79.6 (27.5)

81.8 (27.8)

82.3 (27.9)

78.9 (28.5)

 Protein (g/d)

74.7 (20.8)

76.5 (22.6)

76.7 (20.6)

76.0 (19.9)

74.4 (19.6)

70.1 (20.1)

 Fibre (g/d)

19.1 (7.0)

19.3 (7.7)

19.8 (7.1)

19.6 (6.8)

19.1 (6.6)

17.5 (6.8)

 Energy (kJ/d)

9,090 (2,309)

8,532 (2,249)

9,002 (2,236)

9,223 (2,255)

9,347 (2,290)

9,347 (2,412)

Number of Oxford WebQ

2.2 (1.2)

2.0 (1.1)

2.3 (1.2)

2.4 (1.2)

2.3 (1.2)

2.0 (1.1)

  1. Abbreviations: BMI Body mass index, FS Free sugars, g/d Grams per day, kg/m2 Kilogram per square meter, kJ Kilojoules, MET Metabolic equivalent of task, mmHg Millimetres of mercury, %E Percentage total energy, SBP Systolic blood pressure, SD Standard deviation
  2. *Categorical variables are summarized as frequencies (percentages) and continuous variables as mean (SD)