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Fig. 4 | Nutrition Journal

Fig. 4

From: Pomegranate (Punica granatum L.) peel extract ameliorates metabolic syndrome risk factors in patients with non-alcoholic fatty liver disease: a randomized double-blind clinical trial

Fig. 4

Effects of pomegranate peel on metabolic syndrome risk factors. In this figure, the anti-oxidant, anti-inflammatory, and prebiotic effects of pomegranate peel are illustrated. PP as a prebiotic leads to the production of short-chain fatty acids (SCFA), the reduction of lipopolysaccharides (LPS), and the regulation of GLP-1 secretion. On the other hand, PP resulted in reduced inflammatory pathways and regulated lipolysis and insulin sensitivity. Together, they cause lower cholesterol and blood sugar levels, as well as lower fibrosis in the liver. Also, PP as an antioxidant leads to lower lipotoxicity and regulated lipid-related hormones such as leptin and adiponectin which all result in lower lipid globules in the liver and reduced appetite as well as weight gain

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