Table 2 Association between duration of maternal FA supplementation and occurrence of CHD or ASD
Folic acid intake | Authors (year) | Duration | CHD OR (95% Cl) | ASD OR (95% Cl) |
|---|---|---|---|---|
Intake short-term before pregnancy | Li X et al. (2013) [31] | Before pregnancy ≤ 1 month | 0.60 (0.31, 1.17) | 0.53 (0.27, 1.05) |
Mao B et al. (2017) [34] | Before pregnancy ≤ 2 months | |||
Intake short-term after pregnancy | Li X et al. (2013) [31] | During pregnancy < 1 month | 0.79 (0.42, 1.47) | 0.66 (0.41, 1.07) |
Mao B et al. (2017) [34] | During pregnancy ≤ 3 months | |||
Intake long-term before pregnancy | Li X et al. (2013) [31] | Before pregnancy 1–3 months | 0.39 (0.23, 0.68) | 0.28 (0.13, 0.58) |
Mao B et al. (2017) [34] | Before pregnancy > 2 months | |||
Intake long-term after pregnancy | Li X et al. (2013) [31] | During pregnancy > 1 months | 0.60 (0.43, 0.83) | 0.43 (0.26, 0.70) |
Mao B et al. (2017) [34] | During pregnancy ≥ 3 months |