| Zinc groupa | Placebo groupb | t | df | P-value* | ||||
---|---|---|---|---|---|---|---|---|---|
Baseline | Week 8 | Change | Baseline | Week 8 | Change | ||||
BMI (kg/m2) | 24.36 ± 4.19 | 24.21 ± 4.07 | −0.14 ± 0.72 | 25.50 ± 4.91 | 25.25 ± 5.33 | −0.25 ± 1.65 | 0.36 | 78 | 0.71 |
Zinc (μg/dL) | 85.41 ± 12.87 | 89.52 ± 12.22 | 4.11 ± 5.46c | 84.20 ± 11.65 | 87.07 ± 12.26 | 2.87 ± 7.77a | 0.82 | 78 | 0.41 |
Headache severityd | 7.22 ± 1.14 | 5.47 ± 1.78 | −1.75 ± 1.79c | 6.80 ± 0.93 | 6.00 ± 1.50 | −0.80 ± 1.57a | − 2.51 | 78 | 0.01 |
Attacks frequency (month) | 8.80 ± 6.16 | 6.25 ± 4.38 | − 2.55 ± 4.32c | 9.45 ± 5.39 | 9.02 ± 6.37 | − 0.42 ± 4.24 | − 2.22 | 78 | 0.02 |
Attacks duration (hour) | 17.67 ± 13.59 | 13.92 ± 9.90 | −3.75 ± 7.91c | 22.85 ± 16.47 | 18.65 ± 14.47 | − 4.20 ± 12.04a | 0.19 | 78 | 0.84 |
HDRe | 151.67 ± 138.87 | 94.15 ± 117.42 | − 57.52 ± 91.64c | 198.00 ± 138.98 | 165.45 ± 155.59 | − 32.55 ± 129.22 | − 0.99 | 78 | 0.32 |