Variables | Time of the study | Â | Â | ||
---|---|---|---|---|---|
Beginning of study | End of study | P-valuec | aP-value | bP-value | |
Quality of life questionnaire score | Â | Â | Â | 0.001 | 0.003 |
 Low dose group | 42.59 ± 8.66 | 44.73 ± 8.01 | < 0.001 |  |  |
 High dose group | 40.54 ± 9.46 | 46.75 ± 9.27 | < 0.001 |  |  |
 P-valued | 0.45 | 0.43 |  |  |  |
Clinical Activity Indicator Questionnaire score | Â | Â | Â | 0.004 | 0.045 |
 Low dose group | 3.00 ± 3.59 | 2.68 ± 2.27 | 0.009 |  |  |
 High dose group | 5.25 ± 2.98 | 2.67 ± 2.25 | < 0.001 |  |  |
 P-valued | 0.06 | 0.98 |  |  |  |