Effect of maternal pre-pregnancy BMI and weekly gestational weight gain on the development of infants

Li, Chao; Zeng, Lingxia; Wang, Duolao; Dang, Shaonong; Chen, Tao; Watson, Victoria; Yan, Hong

doi:10.1186/s12937-019-0432-8

Nutrition Journal

Table 2 Association between maternal pre-pregnancy BMI and development of infants ^a

From: Effect of maternal pre-pregnancy BMI and weekly gestational weight gain on the development of infants

	Maternal pre-pregnancy BMI
	Unadjusted analysis		Model 1 ^b		Model 2 ^c
	Coef(95%CI)	P	Coef(95%CI)	P	Coef(95%CI)	P
Age of 3 months
WAZ	0.07(0.04,0.09)	< 0.001	0.07(0.04,0.10)	< 0.001	0.07(0.05,0.10)	< 0.001
LAZ	0.04(0.01,0.07)	0.027	0.04(0.01,0.07)	0.016	0.04(0.01,0.07)	0.013
WLZ	0.05(0.02,0.08)	0.002	0.06(0.02,0.09)	0.001	0.06(0.02,0.09)	0.001
MDI	0.34(−0.19,0.87)	0.204	0.47(− 0.06,1.00)	0.085	0.39(− 0.14,0.92)	0.145
Age of 6 months
WAZ	0.08(0.06,0.11)	< 0.001	0.09(0.06,0.12)	< 0.001	0.09(0.06,0.12)	< 0.001
LAZ	0.04(0.01,0.07)	0.015	0.05(0.01,0.08)	0.005	0.05(0.02,0.08)	0.004
WLZ	0.08(0.05,0.11)	< 0.001	0.08(0.05,0.11)	< 0.001	0.08(0.05,0.11)	< 0.001
MDI	−0.07(−0.59,0.44)	0.785	0.13(−0.38,0.65)	0.612	0.07(−0.45,0.58)	0.796
Age of 12 months
WAZ	0.05(0.02,0.08)	0.001	0.06(0.03,0.08)	< 0.001	0.06(0.03,0.08)	< 0.001
LAZ	0.04(0.01,0.07)	0.021	0.04(0.01,0.07)	0.012	0.04(0.01,0.08)	0.009
WLZ	0.04(0.01,0.07)	0.008	0.04(0.01,0.08)	0.007	0.04(0.01,0.08)	0.006
MDI	0.12(− 0.39,0.64)	0.638	0.35(− 0.17,0.87)	0.188	0.28(− 0.24,0.80)	0.297
Age of 18 months
WAZ	0.06(0.03,0.09)	< 0.001	0.06(0.03,0.09)	< 0.001	0.06(0.04,0.09)	< 0.001
LAZ	0.01(− 0.03,0.04)	0.694	0.01(− 0.02,0.04)	0.565	0.01(− 0.02,0.04)	0.509
WLZ	0.08(0.04,0.11)	< 0.001	0.08(0.04,0.11)	< 0.001	0.08(0.04,0.11)	< 0.001
MDI	0.01(−0.51,0.53)	0.965	0.13(−0.39,0.65)	0.625	0.06(−0.46,0.58)	0.824
Age of 24 months
WAZ	0.04(0.01,0.07)	0.005	0.05(0.02,0.08)	0.001	0.05(0.02,0.08)	0.001
LAZ	0.01(− 0.02,0.04)	0.530	0.01(− 0.02,0.05)	0.386	0.02(−0.02,0.05)	0.342
WLZ	0.05(0.02,0.08)	0.002	0.05(0.02,0.08)	0.002	0.05(0.02,0.08)	0.002
MDI	0.13(−0.39,0.66)	0.620	0.35(−0.17,0.88)	0.189	0.39(−0.24,0.81)	0.281
Total
WAZ	0.06(0.04,0.08)	< 0.001	0.07(0.04,0.09)	< 0.001	0.07(0.04,0.09)	< 0.001
LAZ	0.03(0.01,0.05)	0.044	0.03(0.01,0.06)	0.021	0.03(0.01,0.06)	0.016
WLZ	0.06(0.04,0.08)	< 0.001	0.06(0.04,0.08)	< 0.001	0.06(0.04,0.08)	< 0.001
MDI	0.10(−0.23,0.44)	0.540	0.28(− 0.04,0.61)	0.089	0.22(− 0.11,0.54)	0.196

Abbreviation: CI confidence interval, LAZ length for age Z scores, MDI mental development index, WAZ weight for age Z scores, WLZ weight for length Z scores
^aGeneralized estimated equation linear model were used to assess the association between maternal pre-pregnancy BMI and development of infants
^bModel 1 include the variables of county, sex of infant, maternal age, educational level of parents, household wealth index, occupation of parents
^cModel 2 include the variables of county, sex of infant, maternal age, educational level of parents, household wealth index, occupation of parents, gestational weeks at birth, gestational weeks when maternal weight measured, maternal pre-pregnancy BMI, type of prenatal micronutrient supplementation, doses of supplements consumed

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