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Table 4 Effect of combining the diagnostic groups together to show Simpson’s paradox

From: Severely malnourished children with a low weight-for-height have a higher mortality than those with a low mid-upper-arm-circumference: I. Empirical data demonstrates Simpson’s paradox

Effect of combining diagnostic groups

Subgroups

Total

dead

CFR

comparisons

p

#

#

%

All-muac v All-whz without oedeam

 M-muac

7191

56

0.78

muac v whz

0.000

 M-whz

16,530

332

2.01

muac v both

0.000

 M-both

40,307

2000

4.96

whz v both

0.000

    

Cramer’s V

0.044

 M-All-muac

47,498

2056

4.33

χ2 = 3.01

0.083

 M-All-whz

56,837

2332

4.10

Cramer’s V

0.005

All-muac v All-whz with oedema

 K-muac

1669

118

7.07

muac v whz

0.000

 K-whz

1088

169

15.53

muac v both

0.000

 K-both

4217

576

13.66

whz v both

0.411

    

Cramer’s V

0.115

 K-All-muac

5886

694

11.79

χ2 = 9.75

0.002

 K-All-whz

5305

745

14.04

Cramer’s V

0.028

All-muac v All-whz with and without oedema

 M + K-muac

8860

174

1.96

muac v whz

0.000

 M + K-whz

17,618

501

2.84

muac v both

0.000

 M + K-both

44,524

2576

5.79

whz v both

0.000

    

Cramer’s V

0.025

 M + K - All-muac

53,384

2750

5.15

χ2 = 2.16

0.141

 M + K - All-whz

62,142

3077

4.95

Cramer’s V

0.004

  1. The effect of grouping M-both and K-both with the single deficits to produce erroneous results due to mathematical coupling. All-muac is defined as M-muac + M-both or K-muac + K-both; All-whz is defined as M-whz + M-both or K-whz + K-both; Cramer’s V (a measure of the degree to which the two categories are associated, 0 = no association, 1 = identity) calculated for MUAC v WHZ only